In order to meet the computational requirements of this family-based type of analysis, researchers modified a previous implementation, so as to allow multi-core parallelization on a high-performance computing system. Although the researchers obtained recombination-rate estimates larger than zero for all but one pair of adjacent markers within the four previously proposed linkage groups, none of the three X STR pairs defining the junctions of these groups yielded a recombination rate estimate of 0.50. Corroborating previous studies, these results thus argue against a simple model of independent X chromosomal linkage groups; moreover, the refined recombination fraction estimates obtained in this study will facilitate the appropriate joint consideration of all 15 investigated markers in forensic analysis. 1 figure (Publisher abstract modified)
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