NCJ Number
255177
Journal
Science International Genetics Supplement Series Volume: 5 Dated: December 2015 Pages: E614-E616
Date Published
December 2015
Length
3 pages
Annotation
This article outlines the desired features of a software package for forensic applications, and the progress made towards those aims with the development of a custom version of NextGENe.
Abstract
The use of a next-generation sequencing (NGS) approach for mitochondrial (mt) DNA analysis in forensic casework is imminent. A feature of the NGS approach is the ability to detect and report mtDNA heteroplasmy, which will significantly enhance the discrimination potential of the testing method. The current article addresses the need for a single software solution that allows for robust and user-friendly analysis of NGS-derived mtDNA sequence, especially when considering heteroplasmy. (publisher abstract modified)
Date Published: December 1, 2015
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