This article reports on a research project that obtained the normal Raman and surface‐enhanced Raman spectrum of three controlled substances: morphine, codeine, and hydrocodone.
The spectra were assigned with the aid of density functional theory. Because of intense fluorescence, normal Raman spectra suffered from poor signal‐to‐noise, even when differential subtraction techniques were used. On the other hand, surface enhancement by Ag nanoparticles both enhanced the Raman signal and suppressed the fluorescence, enabling more sensitive detection and identification. The article also presents a set of discriminant bands, useful for distinguishing the three compounds despite the similarities in their structures. (publisher abstract modified)
Downloads
Similar Publications
- Patterns of Concordance Between Hair Assays and Urinalysis for Cocaine: Longitudinal Analysis of Probationers in Pinellas County, Florida (From The Validity of Self-Reported Drug Use: Improving the Accuracy of Survey Estimates, P 161-199, 1997, Lana Harri
- Trends in Heroin Use Among Arrestees in the Drug Use Forecasting Program
- Legal Coercion and Drug Abuse Treatment: Research Findings and Social Policy Implications