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Categorical Methods for the Interpretation of RNA Profiles as Cell Type Evidence and Their Limitations

NCJ Number
Forensic Science International Genetics Supplement Series Volume: 5 Dated: December 2015 Pages: E305-E307
Jacob de Zoete; James Curran; Marjan Sjerps
Date Published
December 2015
3 pages
This article discusses four popular methods for the interpretation of RNA evidence.

Existing methods for the interpretation of RNA profiles as evidence for the presence of certain cell types aim for making categorical statements. Such statements limit the possibility to report the associated uncertainty. From a statistical point of view, a probabilistic approach is a preferable choice. (publisher abstract modified)