NCJ Number
131272
Journal
Journal of Forensic Sciences Volume: 36 Issue: 4 Dated: (July 1991) Pages: 1229-1233
Date Published
1991
Length
5 pages
Annotation
A case report is presented of a 13-month-old boy in whom multiple cardiac rhabdomyomas (CR) were an incidental finding at autopsy following fatal potassium fluoride poisoning.
Abstract
Cardiac rhabdomyomas are rare lesions forming part of the tuberous sclerosis complex that may be responsible for sudden death. Most significant was the fact that the boy was not known to have cardiac lesion prior to autopsy examination for ingestion of a potassium fluoride containing soldering flux. Further detailed gross examination revealed the presence of scattered facial angiofibromas and slightly flattened gyri on the anterior aspects of both frontal lobes which microscopic examination proved to be cortical tubers. The value of gently palpating the brain for firm areas is emphasized. Particular attention should also be focused on the kidneys, skin, lungs, bones, and eyes in looking for characteristic lesions that may support this diagnosis. The significance of establishing the diagnosis of tuberous sclerosis in a patient in whom cardiac rhabdomyomas have been discovered lies in the inherited nature of 20 to 50 percent of the cases. 3 figures and 15 references (Author abstract modified)