NCJ Number
246150
Journal
Journal of Forensic Sciences Volume: 58 Issue: 4 Dated: July 2013 Pages: 972-980
Date Published
July 2013
Length
9 pages
Annotation
Mitochondrial DNA mtDNA is a valuable tool in the fields of forensic, population, and medical genetics.
Abstract
Mitochondrial DNA mtDNA is a valuable tool in the fields of forensic, population, and medical genetics. However, recording and comparing mtDNA control region or entire genome sequences would be difficult if researchers are not familiar with mtDNA nomenclature conventions. Therefore, mtDNAprofiler, a Web application, was designed for the analysis and comparison of mtDNA sequences in a string format or as a list of mtDNA single-nucleotide polymorphisms mtSNPs. mtDNAprofiler which comprises four mtDNA sequence-analysis tools mtDNA nomenclature, mtDNA assembly, mtSNP conversion, and mtSNP concordance-check supports not only the accurate analysis of mtDNA sequences via an automated nomenclature function, but also consistent management of mtSNP data via direct comparison and validity-check functions. Since mtDNAprofiler consists of four tools that are associated with key steps of mtDNA sequence analysis, mtDNAprofiler will be helpful for researchers working with mtDNA. mtDNAprofiler is freely available at http://mtprofiler.yonsei.ac.kr. Abstract published by arrangement with Wiley.