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PROSPER Community-University Partnership Delivery System Effects on Substance Misuse through 6 1/2; Years Past Baseline from a Cluster Randomized Controlled Intervention Trial

NCJ Number
Preventive Medicine Volume: 56 Issue: 3-4 Dated: 2013 Pages: 190-196
Date Published
7 pages

The authors examine the lasting effects of the PROSPER community-university partnership delivery system on substance misuse for a variety of substances; the authors discuss their methodology and results, as well as research implications.


The authors’ objective for this paper was to examine the effects of a delivery system for evidence-based preventive interventions through 12th grade, 6.5 years past baseline. The study’s cohort sequential design included 28 public school districts randomly assigned to the partnership delivery system or usual-programming conditions. Partnerships supported community teams that implemented a family-focused intervention in sixth grade and a school-based intervention in seventh grade. Outcome measures included lifetime, current misuse, and frequencies of misuse, for a range of substances. The authors conducted intent-to-treat, multilevel analyses of covariance of point-in-time misuse and analyses of growth in misuse. Results showed significantly lower substance misuse in the intervention group at one or both time points for most outcomes, with relative reduction rates of up to 31.4 percent. There was significantly slower growth in misuse in the intervention group for eight of the 10 outcomes. In addition, risk moderation results indicated that there were significantly greater intervention benefits for higher- versus lower-risk youth, for the misuse of six of the 10 substances at 11th grade, illicit substances at 12th grade, and growth in the misuse of illicit substances. The authors conclude that partnership-based delivery systems for brief universal interventions have potential for public health impact by reducing substance misuse among youth, particularly higher-risk youth. Publisher Abstract Provided

Date Published: January 1, 2013