This article compares the advantages and disadvantages of the CPI and LR methods to the RMP method.
Mixed DNA profiles are being encountered more frequently as laboratories analyze increasing amounts of touch evidence. If it is determined that an individual could be a possible contributor to the mixture, it is necessary to perform a statistical analysis to allow an assignment of weight to the evidence. Currently, the combined probability of inclusion (CPI) and the likelihood ratio (LR) are the most commonly used methods to perform the statistical analysis. A third method, random match probability (RMP), is available. This article compares the advantages and disadvantages of the CPI and LR methods to the RMP method. The researchers demonstrate that although the LR method is still considered the most powerful of the binary methods, the RMP and LR methods make similar use of the observed data such as peak height, assumed number of contributors, and known contributors where the CPI calculation tends to waste information and be less informative. Abstract published by arrangement with John Wiley & Sons.
Downloads
Similar Publications
- Application of X-ray photoelectron spectroscopy to examine surface chemistry of cancellous bone and medullary contents to refine bone sample selection for nuclear DNA analysis
- Microscale mRNA Amplification, Separation and Detection for Forensic and Clinical Point-of-Care Applications
- ACE: An ATAK Plugin for Enhanced Acoustic Situational Awareness at the Edge