The purpose of this technology transition workshop is to provide the participants with exposure to newly-developing single nucleotide polymorphism (SNP) analysis methods that may be applicable to forensic testing. This class includes lecture and demonstration activities to illustrate the concepts presented, as well as hands-on instruction of SNP data analysis on the testing platforms presented. The participants perform SNP data analysis on two platforms: a combined oligonucleotide ligase assay (OLA) followed by capillary electrophoresis (CE) and electrospray ionization mass spectrometry (ESI-MS). Participants will evaluate typical results produced from single source and mixed samples on each platform. Students are introduced to additional SNP applications being developed to address more advanced types of forensic analysis, such as, phenotypic markers, other mass spectrometry SNP typing assays, linked SNP panels, combined SNP-STR analysis, and mtDNA typing.
Watch
Similar Publications
- Combining surface-enhanced Raman spectroscopy (SERS) and paper spray mass spectrometry (PS-MS) for illicit drug detection
- Forensic Biology Protocols for Molecular Serology Manual
- Gas chromatography with dual cold electron ionization mass spectrometry and vacuum ultraviolet detection for the analysis of phenylethylamine analogues