NCJ Number
311609
Journal
Genome Biology Dated: 2026
Date Published
February 2026
Abstract
The small amount of fragmented DNA present in rootless hair shafts is unsuitable for many assays, including most PCR-based assays. Thus, rootless hair DNA is often overlooked in biomedical and forensic analysis. Here we apply methods for efficient recovery and sequencing of minute quantities of short, fragmented DNA to single human hair shafts. Using this approach, we characterize DNA fragments in hair shafts. Despite the small quantities of fragmented DNA, we find multi-fold genome coverage can be generated from a few centimeters of most hair shafts – enough to generate accurate genotype calls and statistically compelling evidence for identity or non-identity.
(Publisher abstract provided.)
Date Published: February 1, 2026
Downloads
Similar Publications
- The cross-reactivity of cannabinoid analogs (delta-8-THC, delta-10-THC and CBD), their metabolites and chiral carboxy HHC metabolites in urine of six commercially available homogeneous immunoassays
- Cognitive and contextual influences in determination of latent fingerprint suitability for identification judgments
- Criminal Justice Interventions for Offenders With Mental Illness: Evaluation of Mental Health Courts in Bronx and Brooklyn, New York, Executive Summary