This bulletin, part of BJS' Federal Justice Statistics Series, uses data from the U.S. Marshals Service (USMS), Drug Enforcement Administration (DEA), Executive Office for U.S. Attorneys (EOUSA), Administrative Office of the U.S. Courts (AOUSC), and Federal Bureau of Prisons (BOP) to detail the annual activity, workloads, and outcomes associated with the federal criminal justice system from arrest to imprisonment. Tables and text describe arrests and investigations by law enforcement agency and growth rates by type of offense and federal judicial district. This report examines trends in drug arrests by the DEA. It also provides the number of offenders returning to federal prison within 3 years of release and includes the most recently available data on sentences imposed and their lengths by type of offense. Highlights include: 1) At yearend 2012, 414,065 persons were under some form of federal correctional control 62% were in confinement and 38% were under supervision in the community. 2) Fifteen percent of federal prisoners released in 2010 were returned to federal prison within 3 years. Over half (54%) were returned for supervision violations. 3) In 2012, five federal judicial districts along the U.S.-Mexico border accounted for 60% of federal arrests, 53% of suspects investigated, and 41% of offenders sentenced to prison. 4) In 2012, 3,171 suspects were arrested for a sex offense. Defendants convicted of a felony sex offense were the most likely (97%) to receive a prison sentence following conviction. And, 5) during 2012, 172,248 suspects were booked by the U.S. Marshals Service, a 2% decline from 179,034 booked in 2010.