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Polydrug Intoxication Involving Methoxetamine in a Drugs and Driving Case

NCJ Number
246880
Journal
Journal of Forensic Sciences Volume: 59 Issue: 3 Dated: May 2014 Pages: 854-858
Author(s)
Albert A. Elian M.S.; Jeffery Hackett Ph.D.
Date Published
May 2014
Length
5 pages
Annotation
Methoxetamine RS2-3-methoxyphenyl-2-ethylaminocyclohexanone is becoming a drug of interest among practitioners of forensic toxicology.
Abstract
Methoxetamine RS2-3-methoxyphenyl-2-ethylaminocyclohexanone is becoming a drug of interest among practitioners of forensic toxicology. In this case report, we describe the case background, standard field sobriety tests, sampling, and analysis of this drug in a whole blood sample as well as screening methods and analysis from a driver operating under the influence of intoxicating substances. Methoxetamine was isolated from the blood sample using mixed mode solid phase extraction. After elution and evaporation, the residue was dissolved in mobile phase consisting of acetonitrile and aqueous formic acid for analysis by liquid chromatography-tandem mass spectrometry LC-MS/MS and gas chromatography-mass spectrometry GC-MS. The case sample was found to contain clonazepam, 7-aminoclonazepam, carboxy-THC, Ddphenhydramine, and MDMA. The case sample was found to contain 10 ng/mL of the drug methoxetamine in whole blood. The results of this drug analysis and previous analyses are discussed in terms of this driver operating under the influence of drugs. Abstract published by arrangement with Wiley.