Suicide by Self-Administration of a Drug Mixture Propofol, Midazolam, and Zolpidem in an Anesthesiologist: The First Case Report in Italy

• NCJ Number: 246124
• Journal: Journal of Forensic Sciences Volume: 58 Issue: 3 Dated: May 2013 Pages: 837-841
• Author(s): Anna Pia Colucci, Ph.D.; Roberto Gagliano-Candela, Ph.D.; Lucia Aventaggiato, Ph.D.; Antonio De Donno, M.D., Ph.D.; Sabrina Leonardi, M.D.; Giuseppe Strisciullo, H.S.D.; Francesco Introna, M.D., Ph.D.
• Date Published: May 2013
• Length: 5 pages
• Publication Format: Article
• Publication Type: Case Study
• Language: English
• Country: United States of America

Annotation

The authors report an unusual case of suicide of an anesthesiologist, in which the suicide manner and means depend upon the victim's occupation.

Abstract

This is the first case report published in Italy of a death involving propofol and other drugs. The anesthesiologist was found dead with an empty drip still inserted in the hand and another one near his body. Forensic and toxicological findings suggested that the cause of death was a respiratory depression due to a self-administration of a rapidly infused lethal drug mixture. Analytical drug quantification was performed by gas chromatography-mass spectrometry. Blood analysis revealed: zolpidem (0.86 ug/mL), propofol (0.30 ug/mL), midazolam (0.08 ìg/mL), thiopental (0.03 ug/mL), and amitriptyline (0.07 ug/mL). Adipose tissue and hair analysis suggested a previous and repeated use of these drugs verifying the fact that in Italy recreational abuse of anesthetic and sedative agents in health care practitioners is becoming an increasing problem. Abstract published by arrangement with John Wiley & Sons.