It is stated by the Community Anti-Drug Coalitions of America (CADCA) that the reason this manual was written was to actively involve the business community in the Nation's effort to reduce the devastating effects of drug abuse in the workplace and in the communities. This guide contains information on how to assess the workplace situation. It contains an anonymous employee survey, a discussion of workers' support for drug-free workplace, testimonials, estimated costs of abuse, the importance of the workplace, and benefits of a drug-free workplace. Information is provided on how to set up a drug-free workplace program, with a description of its components such as a substance abuse policy, an employee education program, an employee assistance program, supervisory training, and a drug and alcohol testing program. The different types of drug testing are discussed and program evaluation methods are described, with a review of treatment issues, legal facts, and frequently asked questions. The process of implementing the program is covered. A section on available resources for setting up the program is provided. A sample of a drug-free workplace policy, a sample of a drug and alcohol testing procedure, a drug and alcohol testing request form, a reasonable cause checklist, a last chance agreement, and a sample employee notification letter are included.