Forensic Science International: Genetics Volume: 10 Dated: May 2014 Pages: 12-16
This study examined 52 SNPs (single nucleotide polymorphisms) of the SNPforID forensic identification panel in order to determine the underlying genetic structure of the five regional groups of the Chilean population.
Key findings from this study include the following: results from a STRUCTURE analysis revealed a homogeneous pattern for the five Chilean groups when these groups were analyzed without using ancestry reference data; and when ancestry reference data were included in the analysis, European and Native American co-ancestry were found in comparable levels in all five regions, while African ancestry accounted for a much small proportion across all regions. The primary aim of this study was to explore the underlying genetic structure of the five regional groups of the Chilean population to determine whether a single database of SNP (single nucleotide polymorphisms) variation would be sufficient to compile allele frequency data without regard for differences in allele frequency distribution across Chilean regions. Data for the study were obtained from 451 urban samples from the North, North-Central, Central, South-Central, and South regions of Chile. The samples were evaluated for the 52 SNPs of the SNPforID forensic identification panel to determine the underlying genetic structure of the country's population. The findings indicate that use of a single allele frequency database for the 52 SNPforID markers will be sufficient for DNA identification of victims in Chile. 2 figures, 2 tables, and 19 references
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