NCJ Number
172007
Journal
Journal of Forensic Sciences Volume: 42 Issue: 5 Dated: (September 1997) Pages: 846-849
Date Published
1997
Length
4 pages
Annotation
This paper presents allele frequency data in African Americans, Caucasians, and Hispanics from the United States for four short tandem repeat loci.
Abstract
The study determined allele frequencies for three tetrameric short tandem repeat (STR) loci HUMTH01, TPOX and CSF1PO and a variable number tandem locus D1S80 in United States Caucasian, African American, and Hispanic sample populations. All loci, except the TPOX locus in the Caucasian sample population, meet Hardy-Weinberg expectations. There is no evidence for association of alleles among the four loci. The allele frequency data are similar to other comparable data within the same major population group. United States African American, Caucasian and Hispanic databases have been established for the four STR loci discussed. Application of the product rule is appropriate for estimating the rarity of a multiple loci profile for these four loci. Generally, there are few differences between subgroups within a major population. Moreover, the STR multiplex methodology provides sufficient resolution to separate the HUMTHO1 9.3 and 10 alleles, is relatively simple, and can be implemented into most application-oriented laboratories at minimal cost. Tables, references