ProSynAR: a reference aware read merger

• NCJ Number: 304567
• Journal: Bioinformatics Volume: 38 Issue: 7 Dated: April 2022 Pages: 2052-2053
• Author(s): Benjamin Crysup; Bruce Budowle; August E. Woerner
• Date Published: April 2022
• Length: 2 pages
• Grant Number(s): 2018-DU-BX-0177
• Sponsoring Agency: National Institute of Justice (NIJ)
• Corporate Author: University of North Texas Health Science Center
• Publication Format: Article
• Publication Type: Research (Applied/Empirical)
• Language: English
• Country: United States of America

Annotation

Since read-merging algorithms that look solely at the reads can misalign and mis-merge the reads (especially near repetitive sequences), the C++ program ProSynAR has been written to take the reads’ position in the reference into account when performing (and deciding whether to perform) a merge.

Abstract

Nix users can retrieve the source from GitHub (https://github.com/Benjamin-Crysup/prosynar). Windows binary available at https://github.com/Benjamin-Crysup/prosynar/releases/download/1.0/prosynar.zip. (Publisher Abstract)